Isotope-coded affinity tags with tunable reactivities for protein footprinting.
Underbakke ES, Zhu Y, Kiessling LL
Angew Chem Int Ed Engl : 47 : 9677-80 : Pending Publication Date



Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets.
Davies DR, Gelinas AD, Zhang C, Rohloff JC, Carter JD, O'Connell D, Waugh SM and 8 others
Proc Natl Acad Sci U S A : November 8, 2012



Measuring the stiffness of bacterial cells from growth rates in hydrogels of tunable elasticity.
Tuson HH, Auer GK, Renner LD, Hasebe M, Tropini C, Salick M, Crone WC, Gopinathan A, Huang KC, Weibel DB
Mol Microbiol : 84 : 874-91 : June 1, 2012



Polyacrylamide hydrogels as substrates for studying bacteria.
Tuson HH, Renner LD, Weibel DB
Chem Commun (Camb) : 48 : 1595-7 : February 1, 2012



Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo.
Zachar Z, Marecek J, Maturo C, Gupta S, Stuart SD, Howell K, Schauble A and 7 others
J Mol Med (Berl) : July 19, 2011



Physicochemical regulation of biofilm formation.
Renner LD, Weibel DB
MRS Bull : 36 : 347-355 : May 1, 2011



P. aeruginosa PilT structures with and without nucleotide reveal a dynamic type IV pilus retraction motor.
Misic AM, Satyshur KA, Forest KT
J Mol Biol. 2010 Jul 30;400(5):1011-21. [Link to article]







Key amino acid residues involved in multi-point binding interactions between brazzein, a sweet protein, and the T1R2-T1R3 human sweet receptor.
Assadi-Porter FM, Maillet EL, Radek JT, Quijada J, Markley JL, Max M
J Mol Biol : 398 : 584-99 : May 14, 2010



Specificity landscapes of DNA binding molecules elucidate biological function.
Carlson CD, Warren CL, Hauschild KE, Ozers MS, Qadir N, Bhimsaria D, Lee Y, Cerrina F, Ansari AZ
Proc Natl Acad Sci U S A : 107 : 4544-9 : March 9, 2010



Disassembly of Escherichia coli RecA E38K/DeltaC17 nucleoprotein filaments is required to complete DNA strand exchange.
Britt RL, Haruta N, Lusetti SL, Chitteni-Pattu S, Inman RB, Cox MM
J Biol Chem : 285 : 3211-26 : January 29, 2010




Role of band 3 in regulating metabolic flux of red blood cells.
Lewis IA, Campanella ME, Markley JL, Low PS
Proc Natl Acad Sci U S A : 106 : 18515-20 : November 3, 2009



Sequencing and analyses of all known human rhinovirus genomes reveal structure and evolution.
Palmenberg AC, Spiro D, Kuzmickas R, Wang S, Djikeng A, Rathe JA, Fraser-Liggett CM, Liggett SB
Science : 324 : 55-9 : April 3, 2009



An amphipathic alpha-helix controls multiple roles of brome mosaic virus protein 1a in RNA replication complex assembly and function.
Liu L, Westler WM, den Boon JA, Wang X, Diaz A, Steinberg HA, Ahlquist P.
PLoS Pathog. 2009 Mar;5(3):e1000351. Epub 2009 Mar 27. [Link to article]




Sequencing and analyses of all known human rhinovirus genomes reveal structure and evolution.
Palmenberg AC, Spiro D, Kuzmickas R, Wang S, Djikeng A, Rathe JA, Fraser-Liggett CM, Liggett SB.
Science. 2009 Apr 3;324(5923):55-9. Epub 2009 Feb 12. [Link to article]






Fabrication of Microbial Biofilm Arrays by Geometric Control of Cell Adhesion.
Eun YJ, Weibel DB.
Langmuir. 2009 Feb 12. [Link to article]





The WAVE/SCAR complex promotes polarized cell movements and actin enrichment in epithelia during C. elegans embryogenesis.
Patel FB, Bernadskaya YY, Chen E, Jobanputra A, Pooladi Z, Freeman KL, Gally C, Mohler WA, Soto MC
Dev Biol : 324 : 297-309 : December 15, 2008




The pipeline. Scientific teaching in practice
Miller S, Pfund C, Pribbenow CM, Handelsman J.
Science. 2008 Nov 28;322(5906):1329-30 [Link to article]



Adipocyte metabolism and obesity.
Attie AD, Scherer PE.
J Lipid Res. 2008 Nov 17. [Link to article]






The interaction between an acidic transcriptional activator and its inhibitor. The molecular basis of Gal4p recognition by Gal80p.
Thoden JB, Ryan LA, Reece RJ, Holden HM.
J Biol Chem. 2008 Oct 31;283(44):30266-72. Epub 2008 Aug 13 [Link to article]






Evolution of our understanding of vitamin D
DeLuca HF.
Nutr Rev. 2008 Oct;66(10 Suppl 2):S73-87. [Link to article]





How to get a cow pregnant
Grow  Magazine, Fall 2008, Wisconsin's Magazine for the Life Sciences 






In Planta Analysis of the Cell Cycle-Dependent Localization of AtCDC48A and Its Critical Roles in Cell Division, Expansion, and Differentiation
Sookhee Park, David Michael Rancour, and Sebastian York Bednarek
Plant Physiology, Sep 2008; 148: 246 - 258. [Link to article]










A Caenorhabditis elegans PUF protein family with distinct RNA binding specificity
Craig R. Stumpf, Judith Kimble, and Marvin Wickens
RNA, Aug 2008; 14: 1550 - 1557. [Link to article]







Structure, mechanism and regulation of pyruvate carboxylase.
Jitrapakdee S, St Maurice M, Rayment I, Cleland WW, Wallace JC, Attwood PV.
Biochem J. 2008 Aug 1;413(3):369-87 [Link to article]






How to make DNA
Grow  Summer 2008, Wisconsin's Magazine for the Life Sciences





A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility
Keller MP, Choi Y, Wang P, Belt Davis D, Rabaglia ME, Oler AT, Stapleton DS, Argmann C, Schueler KL, Edwards S, Steinberg HA, Chaibub Neto E, Kleinhanz R, Turner S, Hellerstein MK, Schadt EE, Yandell BS, Kendziorski C, Attie AD
Genome Res. 2008 May;18(5):706-16. [Link to article]


Direct NMR Detection of the Binding of Functional Ligands to the Human Sweet Receptor, a Heterodimeric Family 3 GPCR
Fariba M. Assadi-Porter, Marco Tonelli, Emeline Maillet, Klaas Hallenga, Outhiriaradjou Benard, Marianna Max,‡ and John L. Markley
J. Am. Chem. Soc., 130 (23), 7212–7213, 2008.




The C. elegans SYS-1 protein is a bona fide beta-catenin.
Liu J, Phillips BT, Amaya MF, Kimble J, Xu W.
Dev Cell. 2008 May;14(5):751-61. [Link to article]




Isotope-coded affinity tags with tunable reactivities for protein footprinting.
Underbakke ES, Zhu Y, Kiessling LL.
Angew Chem Int Ed Engl. 2008;47(50):9677-80. [Link to article]




Targeted chemical wedges reveal the role of allosteric DNA modulation in protein-DNA assembly.
Moretti R, Donato LJ, Brezinski ML, Stafford RL, Hoff H, Thorson JS, Dervan PB, Ansari AZ.
ACS Chem Biol. 2008 Apr 18;3(4):220-9. [Link to article]





Structural dependencies of protein backbone 2JNC couplings
Nenad Jurani, J.J. Dannenberg, Gabriel Cornilescu, Pedro Salvador, Elena Atanasova, Hee-Chul Ahn, Slobodan Macura, John L. Markley, Franklyn G. Prendergast.
Protein Sci. 2008 Apr;17(4):768-76. Epub 2008 Feb 27.[Link to article]




Bright ideas for chemical biology.
Lavis LD, Raines RT.
ACS Chem Biol. 2008 Mar 20;3(3):142-55. Review. [Link to article]






A rapid, microplate SNP genotype assay for the leptinob allele.
Oler AT, Attie AD.J
Lipid Res. 2008 May;49(5):1126-9. Epub 2008 Feb 13. 










How to study the smell of cheese
Grow    Winter 2008, Wisconsin's Magazine for the Life Sciences







Synaptotagmin C2A Loop 2 Mediates Ca2+-dependent SNARE Interactions Essential for Ca2+-triggered Vesicle Exocytosis
K. L. Lynch, R.R.L. Gerona, E. C. Larsen, R. F. Marcia, J. C. Mitchell, and T.F.J. Martin
Mol Biol Cell. 2007 Dec;18(12):4957-68. [Link to article]









How to see a protein
Grow    Fall 2007, Wisconsin's Magazine for the Life Sciences







Solid-phase synthesis of alkanethiols for the preparation of self-assembled monolayers.
Derda R, Wherritt DJ, Kiessling LL.
Langmuir. 2007 Oct 23;23(22):11164-7. Epub 2007 Sep 20.[Link to article]





Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme
St Maurice M, Reinhardt L, Surinya KH, Attwood PV, Wallace JC, Cleland WW, Rayment I.
Science. 2007 Aug 24;317(5841):1076-9 [Link to article]





Defined substrates for human embryonic stem cell growth identified from surface arrays.
Derda R, Li L, Orner BP, Lewis RL, Thomson JA, Kiessling LL.
ACS Chem Biol. 2007 May 22;2(5):347-55. [Link to article]





Activating B cell signaling with defined multivalent ligands.
Puffer EB, Pontrello JK, Hollenbeck JJ, Kink JA, Kiessling LL.
ACS Chem Biol. 2007 Apr 24;2(4):252-62. [Link to article]




1,25-Dihydroxyvitamin D3 induces expression of the Wnt signaling co-regulator LRP5 via regulatory elements located significantly downstream of the gene's transcriptional start site.
Fretz JA, Zella LA, Kim S, Shevde NK, Pike JW.
J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):440-5. [Link to article]





ABCA1: at the nexus of cholesterol, HDL and atherosclerosis.
Attie AD.
Trends Biochem Sci. 2007 Apr;32(4):172-9. Epub 2007 Feb 26. Review. [Link to article]






Selective tumor cell targeting using low-affinity, multivalent interactions.
Carlson CB, Mowery P, Owen RM, Dykhuizen EC, Kiessling LL.
ACS Chem Biol. 2007 Feb 20;2(2):119-27. [Link to article]







Regulation of bacterial RecA protein function.
Cox MM.
Crit Rev Biochem Mol Biol. 2007 Jan-Feb;42(1):41-63. Review. [Link to article]








Understanding a transcriptional paradigm at the molecular level. The structure of yeast Gal80p.
Thoden JB, Sellick CA, Reece RJ, Holden HM.
J Biol Chem. 2007 Jan 19;282(3):1534-8. Epub 2006 Nov 22 [Link to article]



Enhancers located in the vitamin D receptor gene mediate transcriptional autoregulation by 1,25-dihydroxyvitamin D3.
Zella LA, Kim S, Shevde NK, Pike JW.
J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):435-9. Epub 2007 Jan 10. [Link to article]



Multiple enhancer regions located at significant distances upstream of the transcriptional start site mediate RANKL gene expression in response to 1,25-dihydroxyvitamin D3.
Kim S, Yamazaki M, Zella LA, Meyer MB, Fretz JA, Shevde NK, Pike JW.
J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):430-4. Epub 2007 Jan 2. [Link to article]





Positional cloning of a type 2 diabetes quanitative trait locus.
Clee, S.M., Yandell, B.S., Schueler, K.M., Rabaglia, M.E., Richards, O.C., Raines, S.M., Kabara, E.A., Klass, D.M., Stapleton, D.S., Gray-Keller, M.P., Boronenkov, I., Raess, P.W., Flowers, M.T., and Attie, A.D.
Nature Genetics 38,688-693 2006[Link to article]





Enhancers located within two introns of the vitamin D receptor gene mediate transcriptional autoregulation by 1,25-dihydroxyvitamin D3.
Zella LA, Kim S, Shevde NK, Pike JW
Mol Endocrinol. 2006 Jun; 20(6):1231-47 [Link to article]








Membrane Association, Mechanism of Action, and Structure of Arabidopsis Embryonic Factor 1 (FAC1)
Byung Woo Han, Craig A. Bingman, Donna K. Mahnke, Ryan M. Bannen, Sebastian Y. Bednarek, Richard L. Sabina, and George N. Phillips, Jr.
J. Biol. Chem., May 2006; 281: 14939 - 14947. [Link to article]
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